Control Study with Pain Relief Medication â€Myassignmenthelp.Com

Question: Discuss About the Control Study with Pain Relief Medication? Answer: Introducation Simpson and Wlodarczyk (2016) conducted a study to examine the efficacy of buprenorphine in patients with DPNP. The authors used a quantitative, multicenter, randomized, double blind control study with pain relief medication and a placebo to establish whether the medication reduced pain among Type 1 and Type 2 diabetic patients with severe to moderate DPNP. Critical to the discussion is the fact that the study design adheres to pragmatic post positivist approach. As evidenced, Creswell (2013) argues that a positivist research always results in the production of credible data, which must always be quantitative. It is notable that the study conducted by Simpson and Wlodarczyk (2016) produced credible and quantitative data. For instance, the authors mention the number of study participants that completed the study. Further, the amount of pain in every participant was measured numerically using a numeric rating scale. In short, the study produced credible and used quantitative data implying it adheres to the approach in question. Simpson and Wlodarczyk (2016) also used a pragmatic approach in the study under discussion. This owes to the fact that Mertens (2015) reveals that a pragmatic study design focusses on the usability of the study results. Specifically, the latter author argues that a pragmatic study design focuses on conducting analyses that should provide information that is understood by the stakeholders. A review of the publication from Simpson and Wlodarczyk (2016) indicates that a common person can understand the study because it begins with a clear objective, procedure, and conclusion. In short, all stakeholders can understand the study implying that it is pragmatic. It is evident that Simpson and Wlodarczyk (2016) could do nothing to improve the study into a pragmatic post positivist approach. It is because their study is uses a pragmatic post positivist approach to answer the clinical question. Regardless, the authors acknowledge that 37 participants in the treatment group and 24 participants from the control group dropped out of the study because of nausea and vomiting. It follows that even though the study cannot be improved into a pragmatic post positivist approach, the authors could reduce nausea and vomiting among the study participants. In particular, a randomized double blind study should be conducted using an anti-nausea medication (such as maxalon) to reduce cases of vomiting and nausea. Apparently, 61 participants dropped out of the study because of nausea and vomiting. According to Rajagopalan, Deodurg, and Srikanth (2013), a large number of participant drop out relative to the sample size could result in sample bias. Considering that a large number of the participants dropped out because of nausea and vomiting introducing anti-nausea into the study would reduce the number of participant drop out and eliminate possible cases of sample bias. In conclusion, it is evident that the study conducted by Simpson and Wlodarczyk (2016) used a pragmatic post positivist approach. This owes to the fact that the study not only, used credible data, but also benefits all stakeholders. However, the study could be improved using a randomized double blind study should be conducted using an anti-nausea medication (such as maxalon) to reduce cases of vomiting and nausea. References Creswell, J. W. (2013).Research design: Qualitative, quantitative, and mixed methods approaches. Thousand Oaks: SAGE Publications Mertens, M, D. (2015). Philosophical Assumptions and Program Evaluation. Retrieved from https://www.spaziofilosofico.it/wp-content/uploads/2015/02/Mertens.pdf Rajagopalan, R., Deodurg, M, P., and Srikanth. (2013). Overview of Randomized Controlled Trials. Asian Journal of Pharmaceutical and Clinical Research, 6(3): 32-38. Retrieved from https://www.ajpcr.com/Vol6Issue3/175.pdf Simpson, R. W., and Wlodarczyk, J. H. (2016). Transdermal Buprenorphine Relieves Neuropathic Pain: A Randomized, Double Blind, Parallel-Group, Placebo-Controlled Trial in Diabetic Peripheral Neuropathic Pain. Diabetes Care, 39(9), 1493-1500. Doi: 10.2337/dc16-0123